Browsing by author "García Osorio, Fernando"

Accelerated ageing: from mechanism to therapy through animal models

García Osorio, Fernando

; Obaya González, Álvaro Jesús

; López Otín, Carlos

; Pérez Freije, José María

(Springer, 2009)

Antisense based therapeutic approaches in Hutchinson-Gilford Progeria

Sandre-Giovannoli, Annachiara de; Navarro Hernández, Carla

; García Osorio, Fernando

; Bartoli, Catherine; Depetris, Danielle; Fayek, R; Pérez Freije, José María

; López Otín, Carlos

; Lévy, Nicolas (2012)

Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations

Rivera Torres, José; Calvo, Conrado J.; Llach, A.; García Osorio, Fernando

; López Otín, Carlos

(2016)

Cell autonomous and systemic factors in progeria development

García Osorio, Fernando

; Piñeiro Ugalde, Alejandro

; Mariño García, Guillermo

; Suárez Puente, Xosé Antón

; Pérez Freije, José María

; López Otín, Carlos

(Portland Press, 2011)

Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver

Whitton, H.; Singh, L. N.; Patrick, M. A.; Price, A. J.; García Osorio, Fernando

; López Otín, Carlos

; Bochkis, I. M. (2018)

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

Varela Egocheaga, Ignacio Alejandro

; Pereira, Sandrine; Piñeiro Ugalde, Alejandro

; Navarro, Claire L.; Fernández Suárez, María

; Cau, Pierre; Cadiñanos Bañales, Juan; García Osorio, Fernando

; Foray, Nicolas; Cobo Plana, Juan Manuel

; Carlos Villafranca, Félix Antonio de

; Lévy, Nicolas; Pérez Freije, José María

; López Otín, Carlos

(2008)

A conserved splicing mechanism of the LMNA gene controls premature aging

López Mejía, Isabel Cristina; Vautrot, Valentin; Toledo, Marion de; Behm-Ansmant, Isabelle; Bourgeois, Cyril F.; Navarro, Claire L.; García Osorio, Fernando

; Pérez Freije, José María

; Stevenin, James; Sandre-Giovannoli, Annachiara de; López Otín, Carlos

(Oxford University Press, 2011)

Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment

Villa Bellosta, Ricardo; Rivera Torres, José; García Osorio, Fernando

; Acín-Pérez, Rebeca; Enríquez, José Antonio; López Otín, Carlos

; Andrés, Vicente (2013)

Deficient autophagy induces chondrocyte dysfunction through lamin a/c accumulation in aging and osteoarthritis

López de Figueroa, P.; Nogueira Recalde, Uxía; Calamia, V.; García Osorio, Fernando

; Lotz, M.; López Otín, Carlos

; Blanco, Francisco J.; Carames, B. (2017)

Deficient autophagy induces chondrocyte senescence through lamin a/c accumulation in aging and osteoarthritis

López de Figueroa, Paloma; Nogueira Recalde, Uxía; Calamia, V.; García Osorio, Fernando

; Lotz, Martin; López Otín, Carlos

; Blanco, Francisco J.; Carames, Beatriz (2017)

Deficient Autophagy Induces Lamin a/C Accumulation in Aging and Osteoarthritis

López de Figueroa, Paloma; Nogueira Recalde, Uxía; García Osorio, Fernando

; Lotz, Martin; López Otín, Carlos

; Blanco, Francisco J.; Carames, Beatriz (2017)

Detection of nuclear envelope alterations in senescence

Bárcena Fernández, Clea

; García Osorio, Fernando

; Pérez Freije, José María

(2013)

Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome

Santiago Fernández, Olaya

; García Osorio, Fernando

; Quesada Fernández, Víctor

; Rodríguez, Francisco; Basso, Sammy; Maeso Miguel, Daniel

; Rolas, Loïc; Barkaway, Anna; Nourshargh, Sussan; Rodríguez Folgueras, Alicia

; Pérez Freije, José María

; López Otín, Carlos

(2019)

Erratum to: NF-¿B activation impairs somatic cell reprogramming in ageing (Nature Cell Biology, (2015), 17, 8, (1004-1013), 10.1038/ncb3207)

Soria Valles, Clara

; García Osorio, Fernando

; Gutiérrez Fernández, Ana Yolanda

; De los Ángeles, A.; Bueno, Clara; Menéndez, P.; Martín Subero, J. I.; Daley, G. Q.; Pérez Freije, José María

; López Otín, Carlos

(2018)

Exome Sequencing and Functional Analysis Identifies BANF1 Mutation as the Cause of a Hereditary Progeroid Syndrome

Suárez Puente, Xosé Antón

; Quesada Fernández, Víctor

; García Osorio, Fernando

; Cabanillas Farpón, Rubén

; Cadiñanos Bañales, Juan; Martínez Fraile, Julia

; Rodríguez Ordóñez, Gonzalo

; Álvarez Puente, Diana

; Fanjul Fernández, Miriam

; Lévy, Nicolas; Pérez Freije, José María

; López Otín, Carlos

; Gutiérrez Fernández, Ana Yolanda

(Elsevier, 2011)

Germ-line mutations in epidermal growth factor receptor (EGFR) are rare but may contribute to oncogenesis: A novel germ-line mutation in EGFR detected in a patient with lung adenocarcinoma

Centeno Ramos, Irene

; Blay Albors, Pilar

; Santamaría Ruiz de Azúa, Íñigo

; Astudillo González, María Aurora

; Sánchez Pitiot, Ana Gloria

; García Osorio, Fernando

; González Arriaga, Patricia

; Iglesias Llaca, Fernando

; Menéndez Rodríguez, María Primitiva

; Tardón García, Adonina

; Pérez Freije, José María

; Balbín Felechosa, Milagros

(BioMed Central, 2011)

Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture

Rivera Torres, José; Acín-Pérez, Rebeca; Cabezas-Sánchez, P.; García Osorio, Fernando

; González-Gómez, Cristina; Megias, D.; Cámara, C.; López Otín, Carlos

; Enríquez, José Antonio; Luque-García, J. L.; Andrés, Vicente (2013)

Immune and inflammatory responses to DNA damage in cancer and aging

Soria Valles, Clara

; López Soto, Alejandro

; García Osorio, Fernando

; López Otín, Carlos

(2017)

Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function

Mariño García, Guillermo

; Piñeiro Ugalde, Alejandro

; Fernández Fernández, Álvaro

; García Osorio, Fernando

; Fueyo Silva, Antonio Manuel

; Pérez Freije, José María

; López Otín, Carlos

(National Academy of Sciences, 2010)

Loss of GLUT4 induces metabolic reprogramming and impairs viability of breast cancer cells

Garrido Cuesta, Pablo

; García Osorio, Fernando

; Morán Suárez, Javier

; Cabello, Estefanía; Alonso García, Ana

; Pérez Freije, José María

; González González, Celestino

(2015)

Browsing by author "García Osorio, Fernando"

Accelerated ageing: from mechanism to therapy through animal models ﻿

Antisense based therapeutic approaches in Hutchinson-Gilford Progeria ﻿

Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations ﻿

Cell autonomous and systemic factors in progeria development ﻿

Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver ﻿

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging ﻿

A conserved splicing mechanism of the LMNA gene controls premature aging ﻿

Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment ﻿

Deficient autophagy induces chondrocyte dysfunction through lamin a/c accumulation in aging and osteoarthritis ﻿

Deficient autophagy induces chondrocyte senescence through lamin a/c accumulation in aging and osteoarthritis ﻿

Deficient Autophagy Induces Lamin a/C Accumulation in Aging and Osteoarthritis ﻿

Detection of nuclear envelope alterations in senescence ﻿

Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome ﻿

Erratum to: NF-¿B activation impairs somatic cell reprogramming in ageing (Nature Cell Biology, (2015), 17, 8, (1004-1013), 10.1038/ncb3207) ﻿

Exome Sequencing and Functional Analysis Identifies BANF1 Mutation as the Cause of a Hereditary Progeroid Syndrome ﻿

Germ-line mutations in epidermal growth factor receptor (EGFR) are rare but may contribute to oncogenesis: A novel germ-line mutation in EGFR detected in a patient with lung adenocarcinoma ﻿

Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture ﻿

Immune and inflammatory responses to DNA damage in cancer and aging ﻿

Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function ﻿

Loss of GLUT4 induces metabolic reprogramming and impairs viability of breast cancer cells ﻿

Accelerated ageing: from mechanism to therapy through animal models

Antisense based therapeutic approaches in Hutchinson-Gilford Progeria

Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations

Cell autonomous and systemic factors in progeria development

Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liver

Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging

A conserved splicing mechanism of the LMNA gene controls premature aging

Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatment

Deficient autophagy induces chondrocyte dysfunction through lamin a/c accumulation in aging and osteoarthritis

Deficient autophagy induces chondrocyte senescence through lamin a/c accumulation in aging and osteoarthritis

Deficient Autophagy Induces Lamin a/C Accumulation in Aging and Osteoarthritis

Detection of nuclear envelope alterations in senescence

Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndrome

Erratum to: NF-¿B activation impairs somatic cell reprogramming in ageing (Nature Cell Biology, (2015), 17, 8, (1004-1013), 10.1038/ncb3207)

Exome Sequencing and Functional Analysis Identifies BANF1 Mutation as the Cause of a Hereditary Progeroid Syndrome

Germ-line mutations in epidermal growth factor receptor (EGFR) are rare but may contribute to oncogenesis: A novel germ-line mutation in EGFR detected in a patient with lung adenocarcinoma

Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture

Immune and inflammatory responses to DNA damage in cancer and aging

Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis function

Loss of GLUT4 induces metabolic reprogramming and impairs viability of breast cancer cells