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Flow cytometric analysis of nuclear DNA content in oral leukoplakia.

dc.contributor.authorSeoane, Juan Manuel
dc.contributor.authorBascones, Antonio
dc.contributor.authorAsenjo, José Antonio
dc.contributor.authorGarcía-Pola Vallejo, María José 
dc.contributor.authorVarela-Centelles, Pablo
dc.date.accessioned2025-01-16T09:20:34Z
dc.date.available2025-01-16T09:20:34Z
dc.date.issued1998-04
dc.identifier.citationClinical Otolaryngology & Alliance Sciences, 23(2), p. 136-40 (1998); doi:10.1046/j.1365-2273.1998.00116.xspa
dc.identifier.issn1749-4478
dc.identifier.urihttps://hdl.handle.net/10651/76237
dc.description.abstractDNA ploidy has been studied in 20 para.n!embedded specimens of oral leukoplakia and in 09 specimens of oral leukoplakia that have undergone malignant transformation after a 4!year observation period[ Three out of 20 specimens "8[6)# showed an aneuploid DNA pattern\ with DNA indices of 0[06\ 0[17 and 0[21[ It was not possible to establish a statistically signi_cant di}erence of DNA ploidy related to the presence or absence of dysplasia[ One out of the 09 oral leukoplakias that underwent malignant transformations had a multiploid pattern with DNA indices of 0[33 and 1[26[ In this study the DNA index has not proved to be of value in the identi_cation of dysplastic leukoplakia among the non!dysplastic ones[spa
dc.format.extentp. 136-140spa
dc.language.isoengspa
dc.relation.ispartofClin Otolaryngol Allied Sci 23(2)spa
dc.rights© 1998 Blackwell Science Ltd
dc.subjectoral leukoplakia, ploidy, flow cytometryspa
dc.titleFlow cytometric analysis of nuclear DNA content in oral leukoplakia.spa
dc.typejournal articlespa
dc.identifier.doi10.1046/j.1365-2273.1998.00116.x
dc.relation.publisherversionhttps://doi.org/10.1046/j.1365-2273.1998.00116.x


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