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CD8+ tumour-infiltrating lymphocytes and tumour microenvironment immune types as biomarkers for Immunotherapy in sinonasal intestinal-type adenocarcinoma

dc.contributor.authorGarcía Marín, Rocío
dc.contributor.authorReda, Sara
dc.contributor.authorRiobello Suárez, Cristina 
dc.contributor.authorNaves Cabal, Virginia
dc.contributor.authorSuárez Fernández, Laura 
dc.contributor.authorVivanco, Blanca
dc.contributor.authorLópez Álvarez, Fernando
dc.contributor.authorLlorente Pendás, José Luis 
dc.contributor.authorHermsen, Mario 
dc.date.accessioned2021-03-16T10:51:34Z
dc.date.available2021-03-16T10:51:34Z
dc.date.issued2020-04-28
dc.identifier.citationVaccines, 8(2) (2020); doi:10.3390/vaccines8020202
dc.identifier.urihttp://hdl.handle.net/10651/58155
dc.description.abstractTMIT classification did not have additional prognostic value over CD8+ TILs alone. The modest percentage of CD8high/PD-L1pos cases indicates that ITAC is a lowly immunogenic tumour type. Nevertheless, a proportion of ITAC, especially the papillary and colonic subtypes, could benefit from therapy with immune checkpoint inhibitors.spa
dc.description.sponsorshipSupported by grants CICPF16008HERM of Fundación AECC, IDI2018/155 Ayudas a Grupos PCTI Principado de Asturias, and CB16/12/00390 from the Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Spain. Plan Nacional de I+D+I 2013-2016 of the Plan Estatal cofinanced by the FEDER Funding Program from the European Union.spa
dc.language.isoengspa
dc.relation.ispartofVaccines,8(2)spa
dc.rightsCC Reconocimiento 4.0 Internacional
dc.rights© 2020 los autores
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectCancer nasosinusalspa
dc.titleCD8+ tumour-infiltrating lymphocytes and tumour microenvironment immune types as biomarkers for Immunotherapy in sinonasal intestinal-type adenocarcinomaspa
dc.typejournal articlespa
dc.identifier.doi10.3390/vaccines8020202
dc.relation.projectIDIDI2018/155
dc.relation.projectIDCB16/12/00390
dc.relation.publisherversionhttps://doi.org/10.3390/vaccines8020202
dc.rights.accessRightsopen accessspa
dc.type.hasVersionVoR


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