New sipanmycin analogues generated by combinatorial biosynthesis and mutasynthesis approaches relying on the substrate flexibility of key enzymes in the biosynthetic pathway

Author:	Gómez Malmierca, Mónica; Pérez Victoria, I.; Martín, Jesús; Reyes, Fernando; Méndez Fernández, María del Carmen; Salas Fernández, José Antonio; Olano Álvarez, Carlos
Publication date:	2020
Publisher version:	http://dx.doi.org/10.1128/AEM.02453-19
Citación:	Applied and Environmental Microbiology, 86(3), p. e02453- (2020); doi:10.1128/AEM.02453-19
Descripción física:	p. e02453-
URI:	http://hdl.handle.net/10651/55321
ISSN:	0099-2240
DOI:	10.1128/AEM.02453-19
Patrocinado por:	This research was supported by grants from the Spanish Ministry of Economy and Competitiveness (grant BIO2015-64161-R to J.A.S.) and MCIU/AEI/FEDER, UE (grant RTI2018- 093562-B-I00 to J.A.S and C.O). The NMR spectrometer used in this work was purchased via a grant for scientific and technological infrastructure from the Ministerio de Ciencia e Innovación (grant PCT-010000-2010-4).
Id. Proyecto:	MINECO/BIO2015-64161-R MCIU/AEI/FEDER/RTI2018-093562-B-I00