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New sipanmycin analogues generated by combinatorial biosynthesis and mutasynthesis approaches relying on the substrate flexibility of key enzymes in the biosynthetic pathway

dc.contributor.authorGómez Malmierca, Mónica 
dc.contributor.authorPérez Victoria, I.
dc.contributor.authorMartín, Jesús
dc.contributor.authorReyes, Fernando
dc.contributor.authorMéndez Fernández, María del Carmen 
dc.contributor.authorSalas Fernández, José Antonio 
dc.contributor.authorOlano Álvarez, Carlos 
dc.date.accessioned2020-06-26T07:57:18Z
dc.date.available2020-06-26T07:57:18Z
dc.date.issued2020
dc.identifier.citationApplied and Environmental Microbiology, 86(3), p. e02453- (2020); doi:10.1128/AEM.02453-19
dc.identifier.issn0099-2240
dc.identifier.urihttp://hdl.handle.net/10651/55321
dc.description.sponsorshipThis research was supported by grants from the Spanish Ministry of Economy and Competitiveness (grant BIO2015-64161-R to J.A.S.) and MCIU/AEI/FEDER, UE (grant RTI2018- 093562-B-I00 to J.A.S and C.O). The NMR spectrometer used in this work was purchased via a grant for scientific and technological infrastructure from the Ministerio de Ciencia e Innovación (grant PCT-010000-2010-4).
dc.format.extentp. e02453-
dc.language.isoeng
dc.relation.ispartofApplied and Environmental Microbiology
dc.rights© 2020 American Society for Microbiology
dc.sourceScopus
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85078554327&doi=10.1128%2fAEM.02453-19&partnerID=40&md5=abb735d90571a7417cdc005a4d644d55
dc.titleNew sipanmycin analogues generated by combinatorial biosynthesis and mutasynthesis approaches relying on the substrate flexibility of key enzymes in the biosynthetic pathway
dc.typejournal article
dc.identifier.doi10.1128/AEM.02453-19
dc.relation.projectIDMINECO/BIO2015-64161-R
dc.relation.projectIDMCIU/AEI/FEDER/RTI2018-093562-B-I00
dc.relation.publisherversionhttp://dx.doi.org/10.1128/AEM.02453-19
dc.rights.accessRightsopen access
dc.type.hasVersionAM


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