Repositorio Institucional de la Universidad de Oviedo

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We thank all members of our laboratory for their helpful comments on the manuscript and apologize for omission of relevant works due to space constraints. Our work is supported by grants from European Union (DeAge, ERC Advanced Grant, ERC 742067); Ministerio de Economia y Competitividad (SAF2014-52413-R); Instituto de Salud Carlos III (PMP15/00007), CIBERONC (ONCG29/2017), Plan Feder; Progeria Research Foundation (PRF 2016-66) and EDP Foundation (Programa EDP SOLIDARIA 2016).