Streptomyces natalensis programmed cell death and morphological differentiation are dependent on oxidative stress

This work was funded by: “NORTE-07-0124-FEDER-000003 – Cell homeostasis tissue organization and organism biology” project co-funded by FEDER funds through the Operational North Region Programme (ON.2 – O Novo Norte) under National Strategic Reference Framework (QREN) and by National funds through FCT – Fundação para a Ciência e Tecnologia/MEC – Ministério da Educação e Ciência and when applicable co-funded by FEDER funds within the partnership agreement PT2020 related with the research unit number 4293. TB was supported by a post-doctoral fellowship under the PEst-C/ SAU/LA0002/2013 (FCOMP-01-0124-FEDER-037277) project; PO, MVM and SDSP were supported by the FCT fellowships SFRH/BPD/74894/2010, SFRH/BPD/95683/2013 and SFRH/BD/66367/2009, respectively. We thank Rui Fernandes, Hugo Osório and Catarina Santos for excellent technical assistance in the preparation of samples for confocal microscopy, protein identification and in silico analysis of the S. natalensis genome, respectively.