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Engineering the Biosynthesis of the Polyketide- Nonribosomal Peptide Collismycin A for Generation of Analogs with Neuroprotective Activity

dc.contributor.authorGarcía Llorente, Ignacio 
dc.contributor.authorMiguel Vior, Natalia 
dc.contributor.authorGonzález Sabín, Javier 
dc.contributor.authorFernández Braña, Alfredo Javier 
dc.contributor.authorRohr, Jürgen
dc.contributor.authorMorís Varas, Francisco
dc.contributor.authorMéndez Fernández, María del Carmen 
dc.contributor.authorSalas Fernández, José Antonio 
dc.date.accessioned2013-11-27T11:28:47Z
dc.date.available2013-11-27T11:28:47Z
dc.date.issued2013
dc.identifier.citationChemistry and Biology, 20(8), p. 1022–1032 (2013); doi:10.1016/j.chembiol.2013.06.014
dc.identifier.issn1074-5521
dc.identifier.urihttp://hdl.handle.net/10651/19686
dc.description.sponsorshipThis research was supported by a grant (to J.A.S.) from the Spanish Ministry of Science and Innovation (BIO2009-07643) and the Plan Regional de Investigación del Principado de Asturias (PC10-05). N.V. was the recipient of a predoctoral fellowship of the Spanish Ministry of Science and Innovation (MICINN, FPI). We are very grateful to Carlos Olano for helpful discussions. We would like to thank Marcos Garcia Ocaña and ZFBiolabs (Madrid, Spain) for helping with the cytotoxicity and zebrafish assays, respectively.
dc.language.isoeng
dc.relation.ispartofChemistry and Biology
dc.rights© 2013 Elsevier Ltd.
dc.sourceSCOPUS
dc.titleEngineering the Biosynthesis of the Polyketide- Nonribosomal Peptide Collismycin A for Generation of Analogs with Neuroprotective Activityeng
dc.typejournal article
dc.identifier.local20130897
dc.identifier.doi10.1016/j.chembiol.2013.06.014
dc.relation.projectIDBIO2009-07643
dc.relation.projectIDPC10-05
dc.relation.publisherversionhttp://dx.doi.org/10.1016/j.chembiol.2013.06.014


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