Engineering the Biosynthesis of the Polyketide- Nonribosomal Peptide Collismycin A for Generation of Analogs with Neuroprotective Activity
Publication date:
2013
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Citación:
Chemistry and Biology, 20(8), p. 1022–1032 (2013); doi:10.1016/j.chembiol.2013.06.014
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Identificador local:
20130897
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This research was supported by a grant (to J.A.S.) from the Spanish Ministry of Science and Innovation (BIO2009-07643) and the Plan Regional de Investigación del Principado de Asturias (PC10-05). N.V. was the recipient of a predoctoral fellowship of the Spanish Ministry of Science and Innovation (MICINN, FPI). We are very grateful to Carlos Olano for helpful discussions. We would like to thank Marcos Garcia Ocaña and ZFBiolabs (Madrid, Spain) for helping with the cytotoxicity and zebrafish assays, respectively.
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