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A novel mithramycin analogue with high antitumor activity and less toxicity generated by combinatorial biosynthesis
| dc.contributor.author | Núñez González, Luz Elena | |
| dc.contributor.author | Nybo, Stephen E. | |
| dc.contributor.author | González Sabín, Javier | |
| dc.contributor.author | Pérez, María | |
| dc.contributor.author | Fernández Braña, Alfredo Javier | |
| dc.contributor.author | Salas Fernández, José Antonio | |
| dc.contributor.author | Méndez Fernández, María del Carmen | |
| dc.date.accessioned | 2013-01-30T10:14:33Z | |
| dc.date.available | 2013-01-30T10:14:33Z | |
| dc.date.issued | 2012 | |
| dc.identifier.citation | Journal of medicinal chemistry, 55(12), p. 5813-5825, (2012); doi:10.1021/jm300234t | spa |
| dc.identifier.issn | 0022-2623 | |
| dc.identifier.uri | http://hdl.handle.net/10651/9627 | |
| dc.description.sponsorship | This work was supported by grants from the National Institutes of Health (Grant CA091901 to J.R.) and the Spanish Ministry of Science and Innovation (Grants BIO2005-04115 and BIO2008-00269 to C.M. and Grant PET2005-0401 to C.M. and F.M.). M.P. was the recipient of a predoctoral fellowship from the Spanish Ministry of Science and Innovation. L.E.N. was the recipient of Torres-Quevedo Program Funding (Grant PTQ04-3-0487) from the Spanish Ministry of Science and Innovation. S.E.N. was partially supported by a graduate fellowship from the University of Kentucky graduate school. | |
| dc.description.statementofresponsibility | Núñez, L.E., Nybo, S.E., González-Sabín, J., Pérez, M., Menéndez, N., Braña, A.F., Shaaban, K.A., He, M., Morí-S, F., Salas, J.A., Rohr, J., Méndez, C. | |
| dc.format.extent | p. 5813-5825 | spa |
| dc.language.iso | eng | |
| dc.relation.ispartof | Journal of medicinal chemistry | spa |
| dc.rights | © 2012 American Chemical Society | |
| dc.source | WOK | spa |
| dc.title | A novel mithramycin analogue with high antitumor activity and less toxicity generated by combinatorial biosynthesis | eng |
| dc.type | journal article | |
| dc.identifier.local | 20120901 | spa |
| dc.identifier.doi | 10.1021/jm300234t | |
| dc.relation.projectID | CA091901 | |
| dc.relation.projectID | BIO2005-04115 | |
| dc.relation.projectID | BIO2008-00269 | |
| dc.relation.projectID | PET2005-0401 | |
| dc.relation.projectID | PTQ04-3-0487 | |
| dc.relation.publisherversion | http://dx.doi.org/10.1021/jm300234t | spa |
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