Mithramycin analogues generated by combinatorial biosynthesis show improved bioactivity
Publication date:
2008
Publisher version:
Citación:
Journal of Natural Products, 71(2), p. 199-207 (2008); doi:10.1021/np0705763
Descripción física:
p. 199-207
ISSN:
Identificador local:
1163
DOI:
Patrocinado por:
This work was supported by grants of the NIH (CA 91901) to J.R., the Spanish Ministry of Education and Science (BIO2005-04115) to C.M., and Red Temática de Investigación Cooperativa de Centros de Cáncer (Ministry of Health, Spain; SCIII-RETICRD06/0020) to J.A.S. We thank the NMR and MS Core Facilities of the University of Kentucky for the use of their instruments and the Nebraska Center for Mass Spectrometry for HRFAB mass spectra. M.P. was the recipient of a predoctoral fellowship of the Spanish Ministry of Science and Technology.
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