| dc.contributor.author | Concellón Gracia, José Manuel | |
| dc.contributor.author | Rivero Espejel, Ignacio Alfredo | |
| dc.contributor.author | Rodríguez Solla, Humberto | |
| dc.contributor.author | Concellón Fernández, María del Carmen | |
| dc.contributor.author | Artega Morales, Estibaly España | |
| dc.contributor.author | García-Granda, Santiago | |
| dc.contributor.author | Díaz Fernández, María del Rosario | |
| dc.date.accessioned | 2013-01-30T10:10:16Z | |
| dc.date.available | 2013-01-30T10:10:16Z | |
| dc.date.issued | 2008 | |
| dc.identifier.citation | Journal of Organic Chemistry, 73(15), p. 6048-6051 (2008); doi:10.1021/jo801058c | spa |
| dc.identifier.issn | 0022-3263 | |
| dc.identifier.uri | http://hdl.handle.net/10651/8861 | |
| dc.description.abstract | The transformation of enantiopure (2R,4R)- and (2S,4S)-N,N-dibenzyl-1,2:4,5-diepoxypentan-3-amine, 1 and 2, into the corresponding enantiopure (3S,5S)- and (3R,5R)-3,5-dihydroxy-3-aminopiperidines, 3 and 4 respectively, is described. The opening of the two epoxide rings with a range of amines takes place with total regioselectivity and high yields, in the presence of LiClO4. A mechanism to explain this transformation is proposed. | spa |
| dc.format.extent | p. 6048-6051 | spa |
| dc.language.iso | eng | |
| dc.relation.ispartof | Journal of Organic Chemistry | spa |
| dc.rights | (c) American Chemical Society | |
| dc.source | WOK | spa |
| dc.title | Totally selective synthesis of enantiopure (3S,5S)and (3R,5R)-4-amino-3,5-dihydroxypiperidines from aminodiepoxides derived from serine | spa |
| dc.type | journal article | |
| dc.identifier.local | 48 | spa |
| dc.identifier.doi | 10.1021/jo801058c | |
| dc.relation.publisherversion | http://dx.doi.org/10.1021/jo801058c | spa |
