Abrogation of stemness in osteosarcoma by the mithramycin analog EC-8042 is mediated by its ability to inhibit NOTCH-1 signaling

Estupiñán Sánchez, Óscar Rafael; Rey, Verónica; Tornín, Juan; Murillo, D.; Gallego, B.; Huergo, C.; Blanco Lorenzo, V.; González Meana, María Victoria; Rodríguez, A.; Moris, F.; González, J.; Ayllón, V.; Ramos Mejía, V.; Bigas, A.; Rodríguez, R.

doi:10.1016/j.biopha.2023.114627

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Abrogation of stemness in osteosarcoma by the mithramycin analog EC-8042 is mediated by its ability to inhibit NOTCH-1 signaling

dc.contributor.author	Estupiñán Sánchez, Óscar Rafael
dc.contributor.author	Rey, Verónica
dc.contributor.author	Tornín, Juan
dc.contributor.author	Murillo, D.
dc.contributor.author	Gallego, B.
dc.contributor.author	Huergo, C.
dc.contributor.author	Blanco Lorenzo, V.
dc.contributor.author	González Meana, María Victoria
dc.contributor.author	Rodríguez, A.
dc.contributor.author	Moris, F.
dc.contributor.author	González, J.
dc.contributor.author	Ayllón, V.
dc.contributor.author	Ramos Mejía, V.
dc.contributor.author	Bigas, A.
dc.contributor.author	Rodríguez, R.
dc.date.accessioned	2023-06-26T09:03:09Z
dc.date.available	2023-06-26T09:03:09Z
dc.date.issued	2023
dc.identifier.citation	Biomedicine and Pharmacotherapy, 162 (2023); doi:10.1016/j.biopha.2023.114627
dc.identifier.issn	0753-3322
dc.identifier.uri	http://hdl.handle.net/10651/68549
dc.description.sponsorship	This work was supported by the Agencia Estatal de Investigación (AEI) [MICINN/Fondo Europeo de Desarrollo Regional (FEDER) (grant PID2019–106666RB-I00 to R.R.) and ISCIII/FEDER (Consorcio CIBERONC - CB16/12/00390)] and the Plan de Ciencia Tecnología e Innovación del Principado de Asturias/FEDER [grant IDI/2021/000027 and Severo Ochoa predoctoral fellowships BP-17–108 to O.E., BP20–046 to B.G. and BP-21–084 to DM].
dc.language.iso	eng
dc.relation.ispartof	Biomedicine and Pharmacotherapy
dc.rights	© 2023 The authors. Published by Elsevier Masson SAS
dc.rights	CC Reconocimiento 4.0 Internacional
dc.rights.uri	http://creativecommons.org/licenses/by/4.0/
dc.source	Scopus
dc.source.uri	https://www.scopus.com/inward/record.uri?eid=2-s2.0-85151414289&doi=10.1016%2fj.biopha.2023.114627&partnerID=40&md5=4d4a70ab26e3ee400e8ff362e73a99f4
dc.title	Abrogation of stemness in osteosarcoma by the mithramycin analog EC-8042 is mediated by its ability to inhibit NOTCH-1 signaling
dc.type	journal article
dc.identifier.doi	10.1016/j.biopha.2023.114627
dc.relation.projectID	MICINN/FEDER/PID2019–106666RB-I00
dc.relation.projectID	ISCIII/FEDER/CB16/12/00390
dc.relation.projectID	FICYT/FEDER/IDI/2021/000027
dc.relation.projectID	Severo Ochoa/BP-17–108
dc.relation.projectID	Severo Ochoa/BP20–046
dc.relation.projectID	Severo Ochoa/BP-21–08
dc.relation.publisherversion	http://dx.doi.org/10.1016/j.biopha.2023.114627
dc.rights.accessRights	open access
dc.type.hasVersion	VoR

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