Is it possible to stage schizophrenia? A systematic review
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A staging model is a clinical tool used to define the development of a disease over time. In schizophrenia, authors have proposed different theoretical staging models of increasing complexity. Therefore, the aims of our study were to provide an updated and critical view of the proposed clinical staging models for schizophrenia and to review the empirical data that support them.
A staging model is a clinical tool used to define the development of a disease over time. In schizophrenia, authors have proposed different theoretical staging models of increasing complexity. Therefore, the aims of our study were to provide an updated and critical view of the proposed clinical staging models for schizophrenia and to review the empirical data that support them.
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This work was partly supported by the Spanish Ministry of Science and Innovation, Instituto de Salud Carlos III (Ref. PI16/01761), the CIBERSAM, Government of the Principality of Asturias (Ref. PCTI-2021-2023 IDI/ 2021/111), and Fondos Europeos de Desarrollo Regional (FEDER). However, the funding sources played no role in this study. Clara Martínez-Cao also thanks the Ministry of Science, Innovation and Universities for its FPU grant (FPU19/01231) and Ainoa Garcia Fernandez thanks Instituto de Salud Carlos III for its PFIS grant (FI20/00318). Spanish Ministry of Science and Innovation, Instituto de Salud Carlos III, Government of the Principality of Asturias and Fondos Europeos de Desarrollo Regional (FEDER).
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