Repositorio Institucional de la Universidad de Oviedo

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This work was supported by the Instituto de Salud Carlos III (ISCIII) (grant number ISCIII/PI17/01424) to JC, co-founded by FEDER. LA-Swas the recipient of a research fellowship by the Ministerio de Ciencia, Innovación y Universidades (grant number FPU18/03243).The authors wish to thank all the Consortia and research groups providing the summary statistics datasets used in this work. Genotyping was performed at CEGEN-PRB3-ISCIII, supported by grant PT17/0019 of the PE I+D+i 2013-2016, funded by ISCIII and ERDF and by Broad Institute. Methylation assays were performed at CEGEN-PRB3-ISCIII. Dr. Vilella's group was supported by the Cerca Pro-gramme (Generalitat de Catalunya). Dr. Bobes and García-Portilla are also grateful for the support of the Government of the Principality ofAsturias PCTI-2018-2022 IDI/2018/235.