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Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

dc.contributor.authorBailey, Mathew H.
dc.contributor.authorMeyerson, William U.
dc.contributor.authorDursi, Lewis Jonathan
dc.contributor.authorLópez Otín, Carlos 
dc.date.accessioned2020-11-13T07:52:27Z
dc.date.available2020-11-13T07:52:27Z
dc.date.issued2020-12
dc.identifier.citationNature Communications, 11(1), p. 4748- (2020); doi:10.1038/s41467-020-18151-y
dc.identifier.issn2041-1723
dc.identifier.urihttp://hdl.handle.net/10651/57047
dc.description.abstractThe Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions.spa
dc.format.extentp. 4748-spa
dc.language.isoengspa
dc.publisherNature Researchspa
dc.relation.ispartofNature Communications, 11(1)spa
dc.rightsCC Reconocimiento 4.0 Internacional
dc.rights© The authors
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es_ES
dc.titleRetrospective evaluation of whole exome and genome mutation calls in 746 cancer samplesspa
dc.typeinfo:eu-repo/semantics/articlespa
dc.type.dcmitextspa
dc.relation.publisherversionhttp://dx.doi.org/10.1038/s41467-020-18151-yspa
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessspa


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