Mostrar el registro sencillo del ítem
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples
dc.contributor.author | Bailey, Mathew H. | |
dc.contributor.author | Meyerson, William U. | |
dc.contributor.author | Dursi, Lewis Jonathan | |
dc.contributor.author | López Otín, Carlos | |
dc.date.accessioned | 2020-11-13T07:52:27Z | |
dc.date.available | 2020-11-13T07:52:27Z | |
dc.date.issued | 2020-12 | |
dc.identifier.citation | Nature Communications, 11(1), p. 4748- (2020); doi:10.1038/s41467-020-18151-y | |
dc.identifier.issn | 2041-1723 | |
dc.identifier.uri | http://hdl.handle.net/10651/57047 | |
dc.description.abstract | The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. | spa |
dc.format.extent | p. 4748- | spa |
dc.language.iso | eng | spa |
dc.publisher | Nature Research | spa |
dc.relation.ispartof | Nature Communications, 11(1) | spa |
dc.rights | CC Reconocimiento 4.0 Internacional | |
dc.rights | © The authors | |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | |
dc.title | Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples | spa |
dc.type | journal article | spa |
dc.relation.publisherversion | http://dx.doi.org/10.1038/s41467-020-18151-y | spa |
dc.rights.accessRights | open access | spa |
dc.type.hasVersion | VoR |
Ficheros en el ítem

Este ítem aparece en la(s) siguiente(s) colección(ones)
-
Artículos [37321]
-
Bioquímica y Biología Molecular [271]