Lipases: Useful biocatalysts for the preparation of pharmaceuticals
Publication date:
2006Publisher version:
https://doi.org/10.1016/j.molcatb.2006.02.010Citación:
Journal of Molecular Catalysis B: Enzymatic, 40(3-4), p. 111-120 (2006); doi:10.1016/j.molcatb.2006.02.010Descripción física:
p. 111-120Abstract:
Biocatalysis offers a clean and ecological way to perform chemical processes, in mild reaction conditions and with high degree of selectivity. The use of enzymes, specially lipases, in organic solvents proves an excellent methodology for the preparation of single-isomer chiral drugs. This review covers some general aspects and representative examples of the use of lipases for the enantioselective or regioselective preparation of alcohol and amine intermediates in the synthesis of pharmaceuticals.
ISSN:
1381-1177Collections
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