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The U1 spliceosomal RNA is recurrently mutated in multiple cancers

dc.contributor.authorShuai, Shimin
dc.contributor.authorSuzuki, Hiromichi
dc.contributor.authorDíaz Navarro, Ander 
dc.contributor.authorNadeu, Ferran
dc.contributor.authorGutiérrez Fernández, Ana Yolanda 
dc.contributor.authorLópez Otín, Carlos 
dc.date.accessioned2020-03-31T07:56:16Z
dc.date.available2020-03-31T07:56:16Z
dc.date.issued2019
dc.identifier.citationNature, 574, p. 712- (2019); doi:10.1038/s41586-019-1651-z
dc.identifier.issn0028-0836
dc.identifier.urihttp://hdl.handle.net/10651/54246
dc.description.sponsorshipThe authors acknowledge the use of pre-embargo whole-genome sequencing alignment data from the PCAWG project, approved by the PCAWG Steering Committee (with L.D.S. recused). This work was supported by the Government of Ontario (S.S. and L.D.S.), the Instituto de Salud Carlos III (project PMP15/00007; to F.N., M.P., J.D., X.S.P., C.L.-O. and E.C.), the 'la Caixa' Foundation Grant No HR17-00221 (Health Research 2017 Program; to F.N., M.P., J.D., X.S.P., C.L.-O. and E.C.) and the Ministerio de Economia y Competitividad (MINECO) SAF2013-45836-R (to X.S.P., A.D.-N. and A.G.-F.). A.D.-N. is supported by the Department of Education of the Basque Government (grant number PRE_2017_1_0100). E.C. is supported by ICREA under the ICREA Academia programme. F.N. is supported by a predoctoral fellowship of the Ministerio de Economia y Competitividad (MINECO, BES-2016076372). H.S. is a recipient of a Research Fellowship (Astellas Foundation for Research on Metabolic Disorders).
dc.description.statementofresponsibilityShuai, SM; Suzuki, H; Diaz-Navarro, A; Nadeu, F; Kumar, SA; Gutierrez-Fernandez, A; Delgado, J; Pinyol, M; Lopez-Otin, C; Puente, XS; Taylor, MD; Campo, E; Stein, LD
dc.format.extentp. 712-spa
dc.language.isoengspa
dc.relation.ispartofNature, 574spa
dc.rights© The Author(s), under exclusive licence to Springer Nature Limited 2019
dc.titleThe U1 spliceosomal RNA is recurrently mutated in multiple cancersspa
dc.typejournal articlespa
dc.relation.projectIDMINECO/SAF2013-45836-R
dc.relation.projectIDMINECO/BES-2016076372
dc.relation.publisherversionhttp://dx.doi.org/10.1038/s41586-019-1651-zspa


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