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Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program

dc.contributor.authorJanin, M.
dc.contributor.authorOrtíz-Barahona, V.
dc.contributor.authorde Moura, M. C.
dc.contributor.authorFernández Fernández, Agustín 
dc.contributor.authorFernández Fraga, Mario 
dc.date.accessioned2019-11-14T10:21:49Z
dc.date.available2019-11-14T10:21:49Z
dc.date.issued2019
dc.identifier.citationActa Neuropathologica, 138, p. 1053–1074 (2019); doi:10.1007/s00401-019-02062-4
dc.identifier.issn0001-6322
dc.identifier.urihttp://hdl.handle.net/10651/53070
dc.description.sponsorshipThis work was supported by a European Research Council (ERC) Advanced Grant under the European Community’s Seventh Framework Program (FP7/2007-2013)/ERC Grant Agreement No. 268626—EPINORC project (to M. Esteller), the Ministerio de Economía y Competitividad (MINECO) under Grant No. SAF2014-55000-R (to M. Esteller) and the Instituto de Salud Carlos III (ISCIII), under the FIS PI16/01278 Project (to J. Seoane), the Integrated Project of Excellence no. PIE13/00022 (ONCOPROFILE) (to M. Esteller), CIBER 2016 CB16/12/00312 (CIBERONC) (to M. Esteller), co-fnanced by the European Development Regional Fund, ‘A way to achieve Europe’ ERDF, the AGAUR—Catalan Government (Project No. 2009SGR1315 and 2014SGR633) (to M. Esteller), the Cellex Foundation (to M. Esteller), Obra Social “La Caixa” (to M. Esteller), the CERCA Program and the Health and Science Departments of the Catalan Government (Generalitat de Catalunya) (to M. Esteller) and a grant from the National Health and Medical Research Council of Australia (APP1061551, to TP). M.W. Boudreau is a member of the NIH Chemistry-Biology Interface Training Program (T32-GM070421).
dc.description.statementofresponsibilityJanin, M., Ortiz-Barahona, V., de Moura, M.C., Martínez-Cardús, A., Llinàs-Arias, P., Soler, M., Nachmani, D., Pelletier, J., Schumann, U., Calleja-Cervantes, M.E., Moran, S., Guil, S., Bueno-Costa, A., Piñeyro, D., Perez-Salvia, M., Rosselló-Tortella, M., Piqué, L., Bech-Serra, J.J., De La Torre, C., Vidal, A., Martínez-Iniesta, M., Martín-Tejera, J.F., Villanueva, A., Arias, A., Cuartas, I., Aransay, A.M., La Madrid, A.M., Carcaboso, A.M., Santa-Maria, V., Mora, J., Fernandez, A.F., Fraga, M.F., Aldecoa, I., Pedrosa, L., Graus, F., Vidal, N., Martínez-Soler, F., Tortosa, A., Carrato, C., Balañá, C., Boudreau, M.W., Hergenrother, P.J., Kötter, P., Entian, K.-D., Hench, J., Frank, S., Mansouri, S., Zadeh, G., Dans, P.D., Orozco, M., Thomas, G., Blanco, S., Seoane, J., Preiss, T., Pandolfi, P.P., Esteller, M.
dc.format.extentp. 1053–1074
dc.language.isoeng
dc.relation.ispartofActa Neuropathologica
dc.rights© The Author(s) 2019
dc.rightsCC Reconocimiento 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceScopus
dc.source.urihttps://www2.scopus.com/inward/record.uri?eid=2-s2.0-85070822137&doi=10.1007%2fs00401-019-02062-4&partnerID=40&md5=477e861c332325d8f0738947fbd8dd35
dc.titleEpigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program
dc.typejournal article
dc.identifier.doi10.1007/s00401-019-02062-4
dc.relation.projectIDISCIII/FIS PI16/01278
dc.relation.projectIDMINECO/SAF2014-55000-R
dc.relation.publisherversionhttp://dx.doi.org/10.1007/s00401-019-02062-4
dc.rights.accessRightsopen access
dc.type.hasVersionVoR


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