Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells

Work in VA’s laboratory is supported by grants from the Spanish Instituto de Salud Carlos III (RD12/0042/0028, AC17/00067 and AC16/00091) and Ministerio de Ciencia, Innovación y Universidades (MCIU) (SAF2016-79490-R), with cofunding from the Fondo Europeo de Desarrollo Regional (FEDER, “Una manera de hacer Europa”), the Progeria Research Foundation (Established Investigator Award 2014-52), and the Fundació Marató TV3 (122/C/2015). The CNIC is supported by the MCIU and the Pro CNIC Foundation, and is a Severo Ochoa Center of Excellence (SEV-2015-0505). Work in the Lopez-Otin laboratory is supported by grants from the Ministerio de Economía y Competitividad (MINECO/FEDER), the European Research Council, and the Progeria Research Foundation. The Instituto Universitario de Oncología is supported by Obra Social Cajastur. Work in the Misteli laboratory was supported by the Intramural Research Program of the National Institutes of Health, National Cancer Institute, and Center for Cancer Research. The MCIU supported RVB (“Juan de la Cierva” JCI-2011-09663 and SAF-2014-60699-JIN postdoctoral contracts) and MRH (FPI predoctoral contract BES-2011-043938 and “Juan de la Cierva” FJCI2017-33299 postdoctoral contract). RMN is supported by the Ministerio de Educación, Cultura y Deporte (FPU predoctoral contract FPU16/05027). VQ is supported by grants from the Principado de Asturias and MINECO, including FEDER funding. SV was supported by an Erwin Schroedinger Fellowship from the Austrian Science Fund (J3849-B28).