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Vascular Smooth Muscle-Specific Progerin Expression Accelerates Atherosclerosis and Death in a Mouse Model of Hutchinson-Gilford Progeria Syndrome

dc.contributor.authorHamczyk, Magda Rita 
dc.contributor.authorVilla Bellosta, Ricardo
dc.contributor.authorGonzalo, Pilar
dc.contributor.authorAndrés Manzano, María J.
dc.contributor.authorNogales, Paula
dc.contributor.authorBentzon, Jacob F.
dc.contributor.authorLópez Otín, Carlos 
dc.contributor.authorAndrés, Vicente
dc.date.accessioned2018-11-27T08:03:38Z
dc.date.available2018-11-27T08:03:38Z
dc.date.issued2018
dc.identifier.citationCirculation, 138(3), p. 266-282 (2018); doi:10.1161/CIRCULATIONAHA.117.030856
dc.identifier.issn0009-7322
dc.identifier.issn1524-4539
dc.identifier.urihttp://hdl.handle.net/10651/49319
dc.description.sponsorshipWork in Dr Andrés’ laboratory is supported by grants from the Spanish Ministerio de Economía, Industria y Competitividad (MEIC) (SAF2016-79490-R) and the Instituto de Salud Carlos III (AC16/00091, AC17/00067) with cofunding from the Fondo Europeo de Desarrollo Regional (FEDER, “Una manera de hacer Europa”), the Progeria Research Foundation (Established Investigator Award 2014-52), and the Fundació Marató TV3 (122/C/2015). The MEIC supported Dr Hamczyk (“Formación de Personal Investigador” predoctoral contract BES-2011–043938) and Dr Villa-Bellosta (“Juan de la Cierva” JCI-2011–09663 postdoctoral contract). The Instituto Universitario de Oncología is supported by Obra Social Cajastur. The Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) is supported by the MEIC and the Pro-CNIC Foundation, and is a Severo Ochoa Center of Excellence (award SEV-2015-0505).
dc.format.extentp. 266-282
dc.language.isoeng
dc.relation.ispartofCirculation
dc.rights© 2018 The Authors. Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.
dc.rightsCC Reconocimiento - No comercial - Sin obras derivadas 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceWOS:000438742400007
dc.titleVascular Smooth Muscle-Specific Progerin Expression Accelerates Atherosclerosis and Death in a Mouse Model of Hutchinson-Gilford Progeria Syndrome
dc.typejournal article
dc.identifier.doi10.1161/CIRCULATIONAHA.117.030856
dc.relation.projectIDSAF2016-79490-R
dc.relation.projectIDAC16/00091, AC17/00067
dc.relation.projectID122/C/2015
dc.relation.projectIDJCI-2011–09663
dc.relation.publisherversionhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.030856
dc.rights.accessRightsopen access


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© 2018 The Authors. Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.
This item is protected with a Creative Commons License