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Clinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia

dc.contributor.authorNadeu, Ferrán
dc.contributor.authorClot, G.
dc.contributor.authorDelgado, J.
dc.contributor.authorSuárez Puente, Xosé Antón 
dc.contributor.authorLópez Otín, Carlos 
dc.date.accessioned2017-12-14T11:04:01Z
dc.date.available2017-12-14T11:04:01Z
dc.date.issued2017
dc.identifier.citationLeukemia,32, p. 645-653(2018); doi:10.1038/leu.2017.291
dc.identifier.issn0390-6078
dc.identifier.urihttp://hdl.handle.net/10651/44859
dc.description.sponsorshipThis study was supported by the Instituto de Salud Carlos III (ISCIII) PMP15/00007; Ministerio de Economía y Competitividad (MINECO) SAF2015-64885-R; Generalitat de Catalunya AGAUR 2014-SGR-795; and Gilead Spain (GLD15/00288). ECa is an Academia Researcher of the 'Institució Catalana de Recerca i Estudis Avançats' (ICREA) of the Generalitat de Catalunya. FN is supported by a pre-doctoral fellowship of the MINECO (BES-2016-076372). We are indebted to the Genomics core facility of the Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS). We are grateful to N Villahoz and MC Muro for their excellent work in the coordination of the CLL Spanish Consortium, and also thank C Capdevila, S Guijarro, L Pla and M Sánchez for their excellent technical assistance. We are also very grateful to all patients with CLL who have participated in this study.
dc.description.statementofresponsibilityNadeu, F., Clot, G., Delgado, J., Martín-García, D., Baumann, T., Salaverria, I., Beà, S., Pinyol, M., Jares, P., Navarro, A., Suárez-Cisneros, H., Aymerich, M., Rozman, M., Villamor, N., Colomer, D., González, M., Alcoceba, M., Terol, M.J., Navarro, B., Colado, E., Payer, Á., Puente, X.S., López-Otín, C., López-Guillermo, A., Enjuanes, A., Campo, E.
dc.format.extentp. 645-653
dc.language.isoeng
dc.relation.ispartofLeukemia
dc.rights© The Author(s) 2017
dc.rightsCC Reconocimiento - No comercial - Sin obras derivadas 4.0 Internacional
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceWOS:000404127001016
dc.titleClinical impact of the subclonal architecture and mutational complexity in chronic lymphocytic leukemia
dc.typejournal article
dc.identifier.doi10.1038/leu.2017.291
dc.relation.projectIDISCII/PMP15/00007
dc.relation.projectIDMINECO/SAF2015-64885-R
dc.relation.projectIDMINECO/BES-2016-076372
dc.relation.publisherversionhttps://doi.org/10.1038/leu.2017.291
dc.rights.accessRightsopen access


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