Autophagy couteracts weight gain, lipotoxicity and pancreatic ß-cell death upon hypercaloric pro-diabetic regimens

GK is supported by the Ligue contre le Cancer (équipe labelisée); Agence National de la Recherche (ANR); Association pour la recherche sur le cancer (ARC); Cancéropôle Ile-de-France; Institut National du Cancer (INCa); Fondation Bettencourt-Schueller; Fondation de France; Fondation pour la Recherche Médicale (FRM); the European Commission (ArtForce); the European Research Council (ERC); the SIRIC Cancer Research and Personalized Medicine (CARPEM); and the Paris Alliance of Cancer Research Institutes (PACRI). PB is supported by a SAF2012-36079 and CDS2010-00045 grants from MINECO, Spain. GM is funded by the Ramon y Cajal Program (RYC-2013-12751) and supported by Spain’s Ministerio de Economía y Competitividad, BFU2015-68539 and the BBVA foundation, BBM_BIO_3105. GM and GK are guarantors of the work presented herein