Identification by genome mining of a type I polyketide gene cluster from Streptomyces argillaceus involved in the biosynthesis of pyridine and piperidine alkaloids argimycins P
Ministry of Economy
This work was supported by grants to CM from the Spanish Ministry of Economy and Competitiveness, MINECO (Grants BIO2011-25398, BIO2014-56752-R and PIM2010EEI-00752) and “Apoyo a grupos de excelencia,” Principado de Asturias-FEDER (FC-15-GRUPIN14-014). EntreChem SL acknowledges funding to the ERA-IB program and MINECO (PIM2010EEI-00752). SY and DZ were recipient of predoctoral fellowships from MINECO. We thank Fundación Bancaria Cajastur for financial support to CO, and we also thank Dr. Fernando Reyes from Fundación Medina, and Dr. Javier González-Sabín and Dr. Nicolás Ríos-Lombardía from Entrechem S.L. for technical support in structural elucidation compounds.