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Synthesis and highly potent hypolipidemic activity of alpha-asarone- and fibrate-based 2-acyl and 2-alkyl phenols as HMG-CoA reductase inhibitors
| dc.contributor.author | Mendieta, A. | |
| dc.contributor.author | Jiménez, F. | |
| dc.contributor.author | Garduño Siciliano, L. | |
| dc.contributor.author | Mojica Villegas, A. | |
| dc.contributor.author | Rosales Acosta, B. | |
| dc.contributor.author | Villa Tanaca, María de Lourdes | |
| dc.contributor.author | Chamorro Cevallos, G. | |
| dc.contributor.author | Medina Franco, J. L. | |
| dc.contributor.author | Meurice, N. | |
| dc.contributor.author | Gutiérrez, R. U. | |
| dc.contributor.author | Montiel, L. E. | |
| dc.contributor.author | Cruz, M. D. C. | |
| dc.contributor.author | Tamariz, J. | |
| dc.date.accessioned | 2017-05-02T12:40:55Z | |
| dc.date.available | 2017-05-02T12:40:55Z | |
| dc.date.issued | 2014 | |
| dc.identifier.citation | Bioorganic and Medicinal Chemistry, 22(21), p. 5871-5882 (2014); doi:10.1016/j.bmc.2014.09.022 | |
| dc.identifier.issn | 0968-0896 | |
| dc.identifier.uri | http://hdl.handle.net/10651/42557 | |
| dc.description.sponsorship | We thank Bruce Allan Larsen for reviewing the use of English in this manuscript. M. C. C. and J.T. gratefully acknowledge Secretaria de Investigacion y Posgrado (SIP)-IPN (Grants 20090326, 20100236, 20110172, 20120830, 20130686, and 20140858) and CONACYT (Grants 80508, 83446, and 178319) for financial support. A. M., A. M.-V., B. R.-A., R. U. G. and L. E. M. thank CONACYT for graduate scholarships awarded and also thank SIP-IPN (PIFI) for a scholarship complement. A. M. also thanks CONACYT (Grant 178319) for a partial scholarship. F.J., L.G.-S., L.V.-T., G. C.-C., M. C. C. and J.T. are fellows of the Estimulos al Desempeno de los Investigadores (EDI)-IPN and Comision de Operacion y Fomento de Actividades Academicas (COFAA)-IPN programs. | |
| dc.format.extent | p. 5871-5882 | |
| dc.language.iso | eng | |
| dc.publisher | Elsevier Ltd | |
| dc.relation.ispartof | Bioorganic and Medicinal Chemistry | |
| dc.rights | © 2014 Elsevier Ltd | |
| dc.source | Scopus | |
| dc.source.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84908433191&doi=10.1016%2fj.bmc.2014.09.022&partnerID=40&md5=bc7f2639dface99bd69ef3e4543ced59 | |
| dc.title | Synthesis and highly potent hypolipidemic activity of alpha-asarone- and fibrate-based 2-acyl and 2-alkyl phenols as HMG-CoA reductase inhibitors | |
| dc.type | journal article | |
| dc.identifier.doi | 10.1016/j.bmc.2014.09.022 | |
| dc.accrualPeriodicity | CONACYT / 83446 | |
| dc.accrualPeriodicity | CONACYT / 178319 | |
| dc.relation.projectID | (SIP)-IPN / 20090326 | |
| dc.relation.projectID | (SIP)-IPN / 20100236 | |
| dc.relation.projectID | (SIP)-IPN / 20110172 | |
| dc.relation.projectID | (SIP)-IPN / 20120830 | |
| dc.relation.projectID | (SIP)-IPN / 20130686 | |
| dc.relation.projectID | (SIP)-IPN / 20140858 | |
| dc.relation.projectID | CONACYT / 80508 | |
| dc.relation.publisherversion | http://dx.doi.org/10.1016/j.bmc.2014.09.022 |
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