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Cloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin

dc.contributor.authorLombó Brugos, Felipe 
dc.contributor.authorSiems, K.
dc.contributor.authorFernández Braña, Alfredo Javier 
dc.contributor.authorMéndez Fernández, María del Carmen 
dc.contributor.authorBindseil, K. U.
dc.contributor.authorSalas Fernández, José Antonio 
dc.date.accessioned2017-02-16T08:46:55Z
dc.date.available2017-02-16T08:46:55Z
dc.date.issued1997
dc.identifier.citationJournal of Bacteriology, 179, 10, p. 3354-3357 (1997); doi:10.1128/jb.179.10.3354-3357.1997
dc.identifier.issn0021-9193
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-0030995327&partnerID=40&md5=7951c6166c87f74383a1a5d1360cab95
dc.identifier.urihttp://hdl.handle.net/10651/40171
dc.description.sponsorshipThis project was supported by grants of the Plan National en Biotecnologia (BI094-0037) and of the European Union (BIOTECH programme PL932067 and Human Capital and Mobility program, network project CT94-0570). F.L. was the recipient of a predoctoral grant from the FICYT, Asturias. We are especially thankful to Carmen Vilches for her help in the early stages of this project. We also wish to thank Alfredo F. Braña for his collaboration in the HPLC analysis. We are also grateful to Lilly Co. for cosmid pKC505 and to Pfizer Co. for the kind gift of mithramycin.
dc.format.extentp. 3354-3357
dc.language.isoeng
dc.relation.ispartofJournal of Bacteriology
dc.rights© 1996 Elsevier Science B.V.
dc.sourceScopus
dc.titleCloning and insertional inactivation of Streptomyces argillaceus genes involved in the earliest steps of biosynthesis of the sugar moieties of the antitumor polyketide mithramycin
dc.typejournal article
dc.identifier.doi10.1128/jb.179.10.3354-3357.1997
dc.relation.projectIDBI094-0037
dc.relation.projectIDBIOTECH / PL932067
dc.relation.projectIDHCM / CT94-0570
dc.relation.publisherversionhttp://dx.doi.org/10.1128/jb.179.10.3354-3357.1997


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