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The novel hybrid antitumor compound premithramycinone H provides indirect evidence for a tricyclic intermediate of the biosynthesis of the aureolic acid antibiotic mithramycin

Author:
Lombó Brugos, FelipeUniovi authority; Künzel, Eva; Prado Álvarez, LauraUniovi authority; Fernández Braña, Alfredo JavierUniovi authority; Bindseil, K. U.; Frevert, J.; Bearden, D. W.; Méndez Fernández, María del CarmenUniovi authority; Salas Fernández, José AntonioUniovi authority; Rohr, Jürgen
Publication date:
2000
Publisher version:
http://dx.doi.org/10.1002/(SICI)1521-3773(20000218)39:4<796::AID-ANIE796>3.0.CO;2-N
Citación:
Angewandte Chemie - International Edition, 39, 4, p. 796-799 (2000); doi:10.1002/(SICI)1521-3773(20000218)39:4<796
Descripción física:
p. 796-799
URI:
http://hdl.handle.net/10651/40167
ISSN:
1433-7851
DOI:
10.1002/(SICI)1521-3773(20000218)39:4<796::AID-ANIE796>3.0.CO;2-N
Patrocinado por:

This work was supported by the European Union (BIO4-CT96-0068), the Medical University of South Carolina (Institutional Research Funds of 1999-2 000), and the Spanish Ministry of Education and Culture (BIO97-0771). Dr. M. Walla and Dr. W. Cotham (University of South Carolina) are acknowledged for excellent mass spectra.

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