The novel hybrid antitumor compound premithramycinone H provides indirect evidence for a tricyclic intermediate of the biosynthesis of the aureolic acid antibiotic mithramycin

This work was supported by the European Union (BIO4-CT96-0068), the Medical University of South Carolina (Institutional Research Funds of 1999-2 000), and the Spanish Ministry of Education and Culture (BIO97-0771). Dr. M. Walla and Dr. W. Cotham (University of South Carolina) are acknowledged for excellent mass spectra.

Repositorio Institucional de la Universidad de Oviedo

The novel hybrid antitumor compound premithramycinone H provides indirect evidence for a tricyclic intermediate of the biosynthesis of the aureolic acid antibiotic mithramycin

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