Mostrar el registro sencillo del ítem
Electrocatalytic adsorptive voltammetry for fludarabine determination in urine
| dc.contributor.author | Santos Álvarez, Noemí de los | |
| dc.contributor.author | Lobo Castañón, María Jesús | |
| dc.contributor.author | Miranda Ordieres, Arturo José | |
| dc.contributor.author | Tuñón Blanco, Paulino | |
| dc.date.accessioned | 2015-09-22T10:14:39Z | |
| dc.date.available | 2015-09-22T10:14:39Z | |
| dc.date.issued | 2004 | |
| dc.identifier.citation | Analytica Chimica Acta, 504(2), p. 271-275 (2004); doi:10.1016/j.aca.2003.10.055 | |
| dc.identifier.issn | 0003-2670 | |
| dc.identifier.issn | 1873-4324 | |
| dc.identifier.uri | http://hdl.handle.net/10651/33259 | |
| dc.description.abstract | Fludarabine (F-Ara-A, 9-beta-D-arabinofuranosyl-2-fluoroadenine) is an arabinosyl nucleoside with potent cytotoxic activity against chronic lymphocytic leukemia. Herein, its electrochemical behavior is investigated on pyrolytic graphite electrodes (PGEs); and a novel catalytic adsorptive differential-pulse-voltammetric method for its determination is developed based on the strong electrocatalytic effect on nicotinamide adenine dinucleotide (NADH) oxidation exhibited by the oxidation products of F-Ara-A. This approach was applied to human urine samples, which required a previous solid-phase extraction. The F-Ara-A recovery was of 89.7%. The method proposed is fast, simple and permits detection of F-Ara-A concentrations up to 72 h after infusion | spa |
| dc.description.sponsorship | Authors thank FICYT for financial support (Project No.PB-EXP01-28) and Electroanalysis group members for supplyinghuman urine samples. | |
| dc.format.extent | pp. 271-275 | spa |
| dc.language.iso | eng | spa |
| dc.publisher | Elsevier | |
| dc.relation.ispartof | Analytica Chimica Acta 504(2) | spa |
| dc.subject | Fludarabine | spa |
| dc.subject | Catalytic adsorptive voltammetry | spa |
| dc.title | Electrocatalytic adsorptive voltammetry for fludarabine determination in urine | spa |
| dc.type | journal article | |
| dc.identifier.doi | 10.1016/j.aca.2003.10.055 | |
| dc.relation.publisherversion | http://dx.doi.org/10.1016/j.aca.2003.10.055 | spa |
Ficheros en el ítem
| Ficheros | Tamaño | Formato | Ver |
|---|---|---|---|
|
No hay ficheros asociados a este ítem. |
|||
Este ítem aparece en la(s) siguiente(s) colección(ones)
-
Artículos [37321]