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Adenylation and S -methylation of cysteine by the bifunctional enzyme TioN in thiocoraline biosynthesis

Author:
Al-Mestarihi, A. H.; Villamizar Rodríguez, GermánUniovi authority; Fernández Braña, Alfredo JavierUniovi authority; Zolova, Olga E.; Lombó Brugos, FelipeUniovi authority; Garneau-Tsodikova, Sylvie
Publication date:
2014
Publisher version:
http://dx.doi.org/10.1021/ja510489j
Citación:
Journal of the American Chemical Society, 136(49), p. 17350-17354 (2014); doi:10.1021/ja510489j
Descripción física:
p. 17350-17354
URI:
http://hdl.handle.net/10651/30203
ISSN:
0002-7863
DOI:
10.1021/ja510489j
Patrocinado por:

This project was supported by a NSF CAREER Award MCB-1149427 (to S.G.-T.), by startup funds from the College of Pharmacy at the University of Kentucky (to S.G.-T.). G.V. was supported by a fellowship from project PEST08-17 from FICYT (Government of Asturias) and J.F. was supported by a fellowship from project AGL2010-20622 from MICINN(Government of Spain). We thank Dr. Michael G. Thomas(University of Wisconsin-Madison, WI) for the gift of the BL21(DE3)ybdZ::aac(3)IV bacterial strain. We thank Dr. Oleg V.Tsodikov for critical reading of the manuscript.

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