Aplicaciones de la estereología en Psicobiología

Abstract

The recent applications of the stereology in the neurocience has permitted to accomplish unbiased estimates of numerous morphologic parameters of the Nervous System. This work intends to analyze the precision of the stereological estimations in two psicobiological studies: numerical and volumetric quantifications of nervous cells applying two stereological techniques: the optical fractionator and the Cavalieri's principle. The precision of these estimates depends on two sources on variation: the biological variation (intrinsic to the object of study) and the stereological (caused by the employed techniques). In the text is discussed how to optimize the efficiency of the estimates attending to these two sources of variation.