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First Desymmetrization of 1,3-Propanediamine Derivatives in Organic Solvent. Development of a New Route for the Preparation of Optically Active Amines§

dc.contributor.authorBusto García, Benjamín Eduardo 
dc.contributor.authorGotor Fernández, Vicente 
dc.contributor.authorGarcía-Granda, Santiago 
dc.contributor.authorGotor Santamaría, Vicente Miguel 
dc.date.accessioned2020-05-20T09:21:55Z
dc.date.available2020-05-20T09:21:55Z
dc.date.issued2007
dc.identifier.citationOrganic Letters, 9(21), p. 4203–4206 (2007); doi:10.1021/ol701720m
dc.identifier.issn1523-7060
dc.identifier.urihttp://hdl.handle.net/10651/54887
dc.description.abstractThe chemical synthesis and enzymatic desymmetrization of a panel of prochiral diamines have been successfully described for the first time using lipases in organic solvents. A family of 2-aryl-1,3-propanediamines has been obtained with high enantiopurity and good yields in the PSL-catalyzed reaction using diallyl carbonate in 1,4-dioxane.spa
dc.format.extentp. 4203–4206spa
dc.language.isoengspa
dc.relation.ispartofOrganic Letters, 9spa
dc.rights© 2007 American Chemical Society
dc.titleFirst Desymmetrization of 1,3-Propanediamine Derivatives in Organic Solvent. Development of a New Route for the Preparation of Optically Active Amines§spa
dc.typejournal articlespa
dc.identifier.doi10.1021/ol701720m
dc.relation.publisherversionhttps://doi.org/10.1021/ol701720mspa


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