Browsing by author "Morís Varas, Francisco"

A novel LysR-type regulator negatively affects biosynthesis of the immunosuppressant brasilicardin

Wolanski, M.; Krawiec, M.; Schwarz, P. N.; Stegmann, E.; Wohlleben, W.; Buchmann, A.; Gross, H.; Eitel, M.; Koch, P.; Botas Muñoz, Alma María

; Méndez Fernández, María del Carmen

; Núñez González, Luz Elena

; Morís Varas, Francisco; Fernández Cortés, Jesús

; Zakrzewska-Czerwinska, J. (2020)

The activity of a novel mithramycin analog is related to its binding to DNA, cellular accumulation, and inhibition of Sp1-driven gene transcription

Fernández Guizán, Azahara

; Mansilla Barrado, Sylvia; Barceló, Francisca; Vizcaíno, Carolina; Núñez González, Luz Elena

; Morís Varas, Francisco; González Rodríguez, Segundo

; Portugal Minguela, José (2014)

Aldh1 Expression and Activity Increase during Tumor Evolution in Sarcoma Cancer Stem Cell Populations

Martínez Cruzado, Lucía

; Tornin Cavielles, Juan; Santos Duque, Laura

; Rodríguez García, Aida

; García Castro, Javier; Morís Varas, Francisco; Rodríguez González, René

(2016)

Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer

Cuenca López, María D.; Serrano Heras, Gemma; Montero, Juan Carlos; Corrales Sánchez, Verónica; Gómez Juárez, Mónica; Gascón Escribano, María José; Morales, Jorge Carlos; Voisin, Veronique; Núñez González, Luz Elena

; Morís Varas, Francisco; Bader, Gary D.; Pandiella, Atanasio; Ocaña, Alberto (Impact Journals LLC, 2015)

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2

Pandiella, Atanasio; Morís Varas, Francisco; Ocaña, Alberto; Núñez González, Luz Elena

; Montero, Juan Carlos (Impact Journals LLC, 2015)

Chemoenzymatic one-pot synthesis in an aqueous medium: combination of metal-catalysed allylic alcohol isomerisation-asymmetric bioamination

Ríos Lombardía, Nicolás

; Vidal Vides, Christian

; Cocina Fernández de Cordoba, María

; Morís Varas, Francisco; García Álvarez, Joaquín

; González Sabín, Javier

(2015)

The chromomycin CmmA acetyltransferase: a membrane-bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin

García Fernández, Beatriz

; González Sabín, Javier

; Menéndez Sánchez, Nuria

; Fernández Braña, Alfredo Javier

; Núñez González, Luz Elena

; Morís Varas, Francisco; Salas Fernández, José Antonio

; Méndez Fernández, María del Carmen

(Wiley Open Access, 2011)

Coly-mycin derivatives

García Llorente, Ignacio

; Miguel Vior, Natalia

; Sialer Guerrero, Carlos Alberto

; González Sabín, Javier

; Fernández Braña, Alfredo Javier

; Méndez Fernández, María del Carmen

; Salas Fernández, José Antonio

; Morís Varas, Francisco (2013-03-12)

Compuestos alcaloides argimicinas producidos por Streptomyces argillaceus y sus usos

Ye Huang, Suhui

; Molloy Galiana, Brian

; Fernández Braña, Alfredo Javier

; Cortes Bargallo, Jesús; Morís Varas, Francisco; Salas Fernández, José Antonio

; Méndez Fernández, María del Carmen

(2017-02-20)

Developing a Biocascade Process: Concurrent Ketone Reduction-Nitrile Hydrolysis of 2-Oxocycloalkanecarbonitriles

Liardo, Elisa

; Ríos Lombardía, Nicolás

; Morís Varas, Francisco; González Sabín, Javier

; Rebolledo Vicente, Francisca

(2016)

Engineering the Biosynthesis of the Polyketide- Nonribosomal Peptide Collismycin A for Generation of Analogs with Neuroprotective Activity

García Llorente, Ignacio

; Miguel Vior, Natalia

; González Sabín, Javier

; Fernández Braña, Alfredo Javier

; Rohr, Jürgen; Morís Varas, Francisco; Méndez Fernández, María del Carmen

; Salas Fernández, José Antonio

(2013)

Enzymatic synthesis of enantiomerically enriched derivatives of cis- and trans-cyclopentane-1,2-diamines

González Sabín, Javier

; Morís Varas, Francisco; Peña González, Carmen

; Quijada Saldaña, Francisco Javier

; Rebolledo Vicente, Francisca

; Gotor Santamaría, Vicente Miguel

(2010-01-21)

Enzymatic transesterification of pharmacologically interesting ß-aminocycloalkanol precursors

González Sabín, Javier

; Ríos Lombardía, Nicolás

; Gotor Santamaría, Vicente Miguel

; Morís Varas, Francisco (2013)

Expanding the Chemical Diversity of the Antitumoral Compound Mithramycin by Combinatorial Biosynthesis and Biocatalysis: The Quest for Mithralogs with Improved Therapeutic Window

Méndez Fernández, María del Carmen

; González Sabín, Javier

; Morís Varas, Francisco; Salas Fernández, José Antonio

(2015)

From a Sequential to a Concurrent Reaction in Aqueous Medium: Ruthenium-Catalyzed Allylic Alcohol Isomerization and Asymmetric Bioreduction

Ríos Lombardía, Nicolás

; Vidal Vides, Christian

; Liardo, Elisa

; Morís Varas, Francisco; García Álvarez, Joaquín

; González Sabín, Javier

(2016)

Generation by mutasynthesis of potential neuroprotectant derivatives of the bipyridyl collismycin A

Sialer Guerrero, Carlos Alberto

; García Llorente, Ignacio

; González Sabín, Javier

; Fernández Braña, Alfredo Javier

; Méndez Fernández, María del Carmen

; Morís Varas, Francisco; Salas Fernández, José Antonio

(2013)

Generation of potent and selective kinase inhibitors by combinatorial biosynthesis of glycosylated indolocarbazoles

Sánchez Reillo, César

; Pérez Salas, Aaroa

; Fernández Braña, Alfredo Javier

; Palomino Schätzlein, Martina; Pineda Lucena, Antonio; Carbajo Martínez, Rodrigo José; Méndez Fernández, María del Carmen

; Morís Varas, Francisco; Salas Fernández, José Antonio

(2009)

Genome-wide modulation of gene transcription in ovarian carcinoma cells by a new mithramycin analogue

Vizcaíno, Carolina; Núñez González, Luz Elena

; Morís Varas, Francisco; Portugal Minguela, José (Public Library of Science, 2014)

Glycosylated indolecarbazoles, method for obtaining same and uses thereof

Pérez Salas, Aaroa

; Sánchez Reillo, César

; Fernández Braña, Alfredo Javier

; Méndez Fernández, María del Carmen

; Salas Fernández, José Antonio

; Morís Varas, Francisco (2011-06-09)

High-quality draft genome sequence of the actinobacterium Nocardia terpenica IFM 0406, producer of the immunosuppressant brasilicardins, using illumina and PacBio technologies

Buchmann, Anina; Eitel, Michael; Koch, Pierre; Schwarz, Paul N.; Stegmann, Evi; Wohlleben, Wolfgang; Wolanski, Marcin; Krawiec, Michal; Zakrzewska Czerwinska, Jolanta; Méndez Fernández, María del Carmen

; Botas Muñoz, Alma María

; Núñez González, Luz Elena

; Morís Varas, Francisco; Fernández Cortés, Jesús

; Gross, Harald S. (American Society for Microbiology, 2016)

Browsing by author "Morís Varas, Francisco"

A novel LysR-type regulator negatively affects biosynthesis of the immunosuppressant brasilicardin ﻿

The activity of a novel mithramycin analog is related to its binding to DNA, cellular accumulation, and inhibition of Sp1-driven gene transcription ﻿

Aldh1 Expression and Activity Increase during Tumor Evolution in Sarcoma Cancer Stem Cell Populations ﻿

Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer ﻿

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2 ﻿

Chemoenzymatic one-pot synthesis in an aqueous medium: combination of metal-catalysed allylic alcohol isomerisation-asymmetric bioamination ﻿

The chromomycin CmmA acetyltransferase: a membrane-bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin ﻿

Coly-mycin derivatives ﻿

Compuestos alcaloides argimicinas producidos por Streptomyces argillaceus y sus usos ﻿

Developing a Biocascade Process: Concurrent Ketone Reduction-Nitrile Hydrolysis of 2-Oxocycloalkanecarbonitriles ﻿

Engineering the Biosynthesis of the Polyketide- Nonribosomal Peptide Collismycin A for Generation of Analogs with Neuroprotective Activity ﻿

Enzymatic synthesis of enantiomerically enriched derivatives of cis- and trans-cyclopentane-1,2-diamines ﻿

Enzymatic transesterification of pharmacologically interesting ß-aminocycloalkanol precursors ﻿

Expanding the Chemical Diversity of the Antitumoral Compound Mithramycin by Combinatorial Biosynthesis and Biocatalysis: The Quest for Mithralogs with Improved Therapeutic Window ﻿

From a Sequential to a Concurrent Reaction in Aqueous Medium: Ruthenium-Catalyzed Allylic Alcohol Isomerization and Asymmetric Bioreduction ﻿

Generation by mutasynthesis of potential neuroprotectant derivatives of the bipyridyl collismycin A ﻿

Generation of potent and selective kinase inhibitors by combinatorial biosynthesis of glycosylated indolocarbazoles ﻿

Genome-wide modulation of gene transcription in ovarian carcinoma cells by a new mithramycin analogue ﻿

Glycosylated indolecarbazoles, method for obtaining same and uses thereof ﻿

High-quality draft genome sequence of the actinobacterium Nocardia terpenica IFM 0406, producer of the immunosuppressant brasilicardins, using illumina and PacBio technologies ﻿

A novel LysR-type regulator negatively affects biosynthesis of the immunosuppressant brasilicardin

The activity of a novel mithramycin analog is related to its binding to DNA, cellular accumulation, and inhibition of Sp1-driven gene transcription

Aldh1 Expression and Activity Increase during Tumor Evolution in Sarcoma Cancer Stem Cell Populations

Antitumor activity of the novel multi-kinase inhibitor EC-70124 in triple negative breast cancer

Antitumoral activity of the mithralog EC-8042 in triple negative breast cancer linked to cell cycle arrest in G2

Chemoenzymatic one-pot synthesis in an aqueous medium: combination of metal-catalysed allylic alcohol isomerisation-asymmetric bioamination

The chromomycin CmmA acetyltransferase: a membrane-bound enzyme as a tool for increasing structural diversity of the antitumour mithramycin

Coly-mycin derivatives

Compuestos alcaloides argimicinas producidos por Streptomyces argillaceus y sus usos

Developing a Biocascade Process: Concurrent Ketone Reduction-Nitrile Hydrolysis of 2-Oxocycloalkanecarbonitriles

Engineering the Biosynthesis of the Polyketide- Nonribosomal Peptide Collismycin A for Generation of Analogs with Neuroprotective Activity

Enzymatic synthesis of enantiomerically enriched derivatives of cis- and trans-cyclopentane-1,2-diamines

Enzymatic transesterification of pharmacologically interesting ß-aminocycloalkanol precursors

Expanding the Chemical Diversity of the Antitumoral Compound Mithramycin by Combinatorial Biosynthesis and Biocatalysis: The Quest for Mithralogs with Improved Therapeutic Window

From a Sequential to a Concurrent Reaction in Aqueous Medium: Ruthenium-Catalyzed Allylic Alcohol Isomerization and Asymmetric Bioreduction

Generation by mutasynthesis of potential neuroprotectant derivatives of the bipyridyl collismycin A

Generation of potent and selective kinase inhibitors by combinatorial biosynthesis of glycosylated indolocarbazoles

Genome-wide modulation of gene transcription in ovarian carcinoma cells by a new mithramycin analogue

Glycosylated indolecarbazoles, method for obtaining same and uses thereof

High-quality draft genome sequence of the actinobacterium Nocardia terpenica IFM 0406, producer of the immunosuppressant brasilicardins, using illumina and PacBio technologies