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Please use this identifier to cite or link to this item: http://hdl.handle.net/10651/8412

Title: New integrated elemental and molecular strategies as a diagnostic tool for the quality of water soluble quantum dots and their bioconjugates
Author(s): Trapiella Alfonso, Laura
Montoro Bustos, Antonio Rafael
Ruiz Encinar, Jorge
Costa Fernández, José Manuel
Pereiro García, María Rosario
Sanz Medel, Alfredo
Issue date: 2011
Publisher version: http://dx.doi.org/10.1039/c0nr00822b
Citation: Nanoscale, 3(3), p. 954-957 (2011); doi:10.1039/c0nr00822b
Format extent: p. 954-957
Abstract: Herein, we demonstrate that both qualitative molecular and quantitative elemental data obtained from size exclusion chromatography coupled online for the first time to both molecular fluorescence and elemental mass spectrometry, respectively, turned out to be critical to evaluate the quality of coatings of quantum dots. Moreover, such an instrumental approach also allowed us to study quantitatively the appropriated bioconjugation of quantum dots to antibodies, a critical step for QDs future use in quantitative fluorescence immunoassays.
URI: http://hdl.handle.net/10651/8412
ISSN: 2040-3364
Local identifier: 20110118
Sponsored: The authors are grateful for financial support of the Spanish Ministry of Education and Science, MEC (CTQ2006-02309), and FEDER program co-financing funds.
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