This research was funded by grant BIO2010-16303 from the DGI, Subdireccion General de Proyectos de Investigacion, MICINN, Spain. A.M. was suppor ted by a postdoctoral grant from the Consejeria de Educacion y Ciencia (Asturias, Spain). Y.J. was supported by a grant from the Danish Research Agency (to O.N.J.). Research in the O.N.J. laboratory is supported by the Lundbeck Foundation and the Danish Research Agency.