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Study of the Chemoselectivity in the Aminolysis Reaction ofMethyl Acrylate Catalysed by Lipase B from Candida antarctica

dc.contributor.authorTorre González, Oliver 
dc.contributor.authorGotor Fernández, Vicente 
dc.contributor.authorAlfonso, Ignacio
dc.contributor.authorGarcía Alles, Luis Fernando
dc.contributor.authorGotor Santamaría, Vicente Miguel 
dc.date.accessioned2020-05-20T07:57:53Z
dc.date.available2020-05-20T07:57:53Z
dc.date.issued2005
dc.identifier.citationAdvanced Synthesis and Catalysis, 347(7-8), p. 1007-1014 (2005); doi:10.1002/adsc.200505025
dc.identifier.issn1615-4150
dc.identifier.urihttp://hdl.handle.net/10651/54876
dc.description.abstractThe aminolysis reaction of methyl acrylate(MA) with N,N-dimethyl-1,3-propanediamine(DMAPA) in organic solvents has been optimised us-ing lipase B from Candida antarctica (CAL-B) as bio-catalyst. A kinetic study about the influence of the re-actant concentrations, organic solvent, temperatureand enzyme form has been developed focused onminimising the formatio n of the Michael additionproducts. The economic efficiency of this processhas been finally investigated by reusing the enzymein the best reaction conditions, thereby observing nosignificant loss of activity after three reaction cycles.spa
dc.format.extentp. 1007-1014spa
dc.language.isoengspa
dc.relation.ispartofAdvanced Synthesis and Catalysisspa
dc.rights© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
dc.titleStudy of the Chemoselectivity in the Aminolysis Reaction ofMethyl Acrylate Catalysed by Lipase B from Candida antarcticaspa
dc.typetextspa
dc.identifier.doi10.1002/adsc.200505025
dc.relation.publisherversionhttps://doi.org/10.1002/adsc.200505025spa


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