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Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes

dc.contributor.authorMueller, S.
dc.contributor.authorEngleitner, T.
dc.contributor.authorMaresch, R.
dc.contributor.authorSierra Zapico, Marta Isabel 
dc.contributor.authorFernández Fraga, Mario 
dc.date.accessioned2018-04-24T09:39:40Z
dc.date.available2018-04-24T09:39:40Z
dc.date.issued2018
dc.identifier.citationNature, 554(7690), p. 62-68 (2018); doi:10.1038/nature25459
dc.identifier.issn280836
dc.identifier.urihttp://hdl.handle.net/10651/46738
dc.description.sponsorshipWe thank the comparative experimental pathology team for discussions, and A. Selmeier, L. Dajka, O. Seelbach, P. Meyer, T. Schmidt, J. Eichinger and T. Stauber for technical assistance as well as M. Reichert for vector constructs. The work was supported by the German Cancer Consortium Joint Funding Program, the Helmholtz Gemeinschaft (PCCC Consortium), the German Research Foundation (SFB1243; A13/A14) and the European Research Council (ERC CoG number 648521).
dc.description.statementofresponsibilityMueller, S., Engleitner, T., Maresch, R., Zukowska, M., Lange, S., Kaltenbacher, T., Konukiewitz, B., Öllinger, R., Zwiebel, M., Strong, A., Yen, H.-Y., Banerjee, R., Louzada, S., Fu, B., Seidler, B., Götzfried, J., Schuck, K., Hassan, Z., Arbeiter, A., Schönhuber, N., Klein, S., Veltkamp, C., Friedrich, M., Rad, L., Barenboim, M., Ziegenhain, C., Hess, J., Dovey, O.M., Eser, S., Parekh, S., Constantino-Casas, F., De La Rosa, J., Sierra, M.I., Fraga, M., Mayerle, J., Klöppel, G., Cadiñanos, J., Liu, P., Vassiliou, G., Weichert, W., Steiger, K., Enard, W., Schmid, R.M., Yang, F., Unger, K., Schneider, G., Varela, I., Bradley, A., Saur, D., Rad, R.
dc.format.extentp. 62-68
dc.language.isoeng
dc.relation.ispartofNature
dc.rights© 2018 Macmillan Publishers Limited, part of Springer Nature.
dc.sourceScopus
dc.source.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85041465932&doi=10.1038%2fnature25459&partnerID=40&md5=ef91af453de39ba6c660a6556278ef28
dc.titleEvolutionary routes and KRAS dosage define pancreatic cancer phenotypes
dc.typejournal article
dc.identifier.doi10.1038/nature25459
dc.relation.projectIDERC CoG/648521
dc.relation.publisherversionhttp://dx.doi.org/10.1038/nature25459


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