This work was supported by project CTQ2016-79015-R by Agencia Estatal de Investigacion (Spain) and FEDER. M. Cruz-Alonso acknowledges funding received by Zinc-net (COST TD1304) for a STSM at BAM (Germany). B. Fernandez acknowledges her contract RYC-2014-14985 to the Spanish Ministry of Economy and Competitiveness through the "Ramon y Cajal Program". L. Alvarez and H. Gonzalez acknowledge financial support from "Fundacion Rafael del Pino" and "Fundacion Ma Cristina Masaveu Peterson". The authors would like to thank M. Daniela Corte and Pablo Isidro Marron from the Biobank (HUCA, Oviedo) for antigen retrieval services and Pablo Garcia Manrique for his valuable support in bioconjugation experiments.