Inhibitor of growth protein 4 interacts with Beclin 1 and represses autophagy

We are grateful to Jean-Christophe Rain, Drs O Geneste and JA Hickman (Institut de Recherche Servier, Croissy sur Seine, France) for sharing data on the Beclin 1 interactome and the Hybrigenics team for excellent technical assistance. We are indebted to Prof. Berth Vogelstein for TP53 and EP300 knockout cells. G.M. is funded by the Ramon y Cajal Program (RYC-2013-12751) and supported by Spain's Ministerio de Economia y Competitividad, BFU2015-68539 and the BBVA foundation, SV-15-FBBVA-2. M. N-S was supported by "Contrato Juan de la Cierva" (JCI-2012-14383) from Ministerio de Economia y Competitividad, Spain. GK is supported by the Ligue contre le Cancer (equipe labelisee); Agence National de la Recherche (ANR) - Projets blancs; ANR under the frame of E-Rare-2, the ERA-Net for Research on Rare Diseases; Association pour la recherche sur le cancer (ARC); Canceropole Ilede-France; Institut National du Cancer (INCa); Institut Universitaire de France; Fondation pour la Recherche Medicale (FRM); the European Commission (ArtForce); the European Research Council (ERC); the LeDucq Foundation; the LabEx Immuno-Oncology; the RHU Torino Lumiere, the SIRIC Stratified Oncology Cell DNA Repair and Tumor Immune Elimination (SOCRATE); the SIRIC Cancer Research and Personalized Medicine (CARPEM); and the Paris Alliance of Cancer Research Institutes (PACRI).