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The activity of a novel mithramycin analog is related to its binding to DNA, cellular accumulation, and inhibition of Sp1-driven gene transcription

dc.contributor.authorFernández Guizán, Azahara 
dc.contributor.authorMansilla Barrado, Sylvia
dc.contributor.authorBarceló, Francisca
dc.contributor.authorVizcaíno, Carolina
dc.contributor.authorNúñez González, Luz Elena 
dc.contributor.authorMorís Varas, Francisco
dc.contributor.authorGonzález Rodríguez, Segundo 
dc.contributor.authorPortugal Minguela, José
dc.date.accessioned2015-03-20T12:41:53Z
dc.date.available2015-03-20T12:41:53Z
dc.date.issued2014
dc.identifier.citationChemico-Biological Interactions, 219, p. 123-132 (2014); doi:10.1016/j.cbi.2014.05.019
dc.identifier.issn0009-2797
dc.identifier.issn1872-7786
dc.identifier.urihttp://hdl.handle.net/10651/30475
dc.description.sponsorshipThis work was supported by grant BFU2010-15518 from the Spanish Ministry of Science and Innovation, and the FEDER program of the European Community, and it was performed within the framework of the ‘‘Xarxa de Referencia en Biotecnologia’’ of the Generalitat de Catalunya. It was also supported by the Principado de Asturias Government through PCTI founds 2006-2009, 80% co-financed with the FEDER Operative Program of the Principado de Asturias 2007-2013 (project FC-11-PC-10-31) and Fondo de Investigaciones Sanitarias (Institute Carlos III) PS09/00420 and PI12/01280. A. F-G. is co-financed by the project COF-11-24 from FICYT. C.V. is recipient of a JAE-Predoc2010 fellowship (CSIC), co-financed by the European Social Fund.
dc.format.extentp. 123-132
dc.language.isoeng
dc.relation.ispartofChemico-Biological Interactions
dc.rights© 2014 Elsevier Ireland Ltd. All rights reserved.
dc.sourceWOS:000345637600014
dc.titleThe activity of a novel mithramycin analog is related to its binding to DNA, cellular accumulation, and inhibition of Sp1-driven gene transcriptioneng
dc.typejournal article
dc.identifier.doi10.1016/j.cbi.2014.05.019
dc.relation.projectIDMICINN/BFU2010-15518
dc.relation.projectIDFC-11-PC-10-31
dc.relation.projectIDFIS-PS09/00420
dc.relation.projectIDFIS-PI12/01280
dc.relation.publisherversionhttp://dx.doi.org/10.1016/j.cbi.2014.05.019


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