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Showing results 16 to 35 of 38
Issue DateTitleAuthor(s)
2011Germ-line mutations in epidermal growth factor receptor (EGFR) are rare but may contribute to oncogenesis: A novel germ-line mutation in EGFR detected in a patient with lung adenocarcinomaCenteno Ramos, Irene; Blay Albors, Pilar; Santamaría Ruiz de Azúa, Íñigo; Astudillo González, María Aurora; Sánchez Pitiot, Ana Gloria; García Osorio, Fernando; González Arriaga, Patricia; Iglesias Llaca, Fernando; Menéndez Rodríguez, María Primitiva; Tardón García, Adonina; Pérez Freije, José María; Balbín Felechosa, Milagros
2013Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell cultureRivera Torres, José; Acín-Pérez, Rebeca; Cabezas-Sánchez, P.; García Osorio, Fernando; González-Gómez, Cristina; Megias, D.; Cámara, C.; López Otín, Carlos; Enríquez, José Antonio; Luque-García, J. L.; Andrés, Vicente
2017Immune and inflammatory responses to DNA damage in cancer and agingSoria Valles, Clara; López Soto, Alejandro; García Osorio, Fernando; López Otín, Carlos
2010Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis functionMariño García, Guillermo; Piñeiro Ugalde, Alejandro; Fernández Fernández, Álvaro; García Osorio, Fernando; Fueyo Silva, Antonio Manuel; Pérez Freije, José María; López Otín, Carlos
2015Loss of GLUT4 induces metabolic reprogramming and impairs viability of breast cancer cellsGarrido Cuesta, Pablo; García Osorio, Fernando; Morán Suárez, Javier; Cabello, Estefanía; Alonso García, Ana; Pérez Freije, José María; González González, Celestino
2015Loss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acidGutiérrez Fernández, Ana Yolanda; Soria Valles, Clara; García Osorio, Fernando; Gutiérrez Abril, Jesús; Garabaya Fernández, Cecilia; Aguirre Quevedo, Alina; Fueyo Silva, Antonio Manuel; Fernández García, María de la Soledad; Suárez Puente, Xosé Antón; López Otín, Carlos
2016Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signalingGarcía Osorio, Fernando; Soria Valles, Clara; Santiago Fernández, Olaya; Pérez Freije, José María; López Otín, Carlos
2016MMP-25 metalloprotease regulates innate immune response through NF-κB signalingSoria Valles, Clara; Gutiérrez Fernández, Ana Yolanda; García Osorio, Fernando; Carrero Muñiz, Dido; Ferrando, Adolfo A.; Colado Varela, Enrique; Fernández García, María de la Soledad; Bonzon-Kulichenko, E.; Vázquez, Jesús; Fueyo Silva, Antonio Manuel; López Otín, Carlos
19-Oct-2015New biological mechanisms and intervention strategies in aging and cancerGarcía Osorio, Fernando
2015NF-?B activation impairs somatic cell reprogramming in ageingSoria Valles, Clara; García Osorio, Fernando; Gutiérrez Fernández, Ana Yolanda; Ángeles, A. de los; Bueno, Clara; Menéndez, P.; Martín Subero, J. I.; Daley, G. Q.; Pérez Freije, José María; López Otín, Carlos
2012NF-kappa B in premature agingGarcía Osorio, Fernando; López Otín, Carlos; Pérez Freije, José María
2012NF-kB in premature agingGarcía Osorio, Fernando; López Otín, Carlos; Pérez Freije, José María
2016NF-κB signaling as a driver of ageingGarcía Osorio, Fernando; Soria Valles, Clara; Santiago Fernández, Olaya; Pérez Freije, José María; López Otín, Carlos
2016The novel tumor suppressor AIRAPL regulates IGF1R proteostasisGarcía Osorio, Fernando; Pérez Freije, José María; López Otín, Carlos
2010Nuclear envelope alterations generate an aging-like epigenetic pattern in mice deficient in Zmpste24 metalloproteaseGarcía Osorio, Fernando; Varela Egocheaga, Ignacio Alejandro; Lara Martín, Ester; Suárez Puente, Xosé Antón; Santoro, Raffaella; Pérez Freije, José María; Fernández Fraga, Mario; López Otín, Carlos
2014Nuclear envelope lamin-A couples actin dynamics with immunological synapse architecture and T cell activationGonzález-Granado, José M.; Silvestre-Roig, Carlos; Rocha-Perugini, Vera; Trigueros-Motos, Laia; Cibrian, Danay; Morlino, Giulia; Blanco-Berrocal, Marta; García Osorio, Fernando; Pérez Freije, José María; López Otín, Carlos; Sánchez-Madrid, Francisco; Andrés, Vicente
2012Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory responseGarcía Osorio, Fernando; Bárcena Fernández, Clea; Soria Valles, Clara; Ramsay, Andrew John; Carlos Villafranca, Félix Antonio de; Cobo Plana, Juan Manuel; Fueyo Silva, Antonio Manuel; Pérez Freije, José María; López Otín, Carlos
1-Jun-2015Nuevas aproximaciones al estudio molecular del envejecimiento: corrección de alteraciones genéticas mediante el empleo del sistema CRISPR/Cas9Santiago Fernández, Olaya
2016Nuevos mecanismos biológicos y estrategias de intervención en envejecimiento y cáncerGarcía Osorio, Fernando
2013Prelamin A causes progeria through cell-extrinsic mechanisms and prevents cancer invasionRosa de Sáa, Jorge de la; Pérez Freije, José María; Cabanillas Farpón, Rubén; García Osorio, Fernando; Fernández Fraga, Mario; Fernández García, María de la Soledad; Rad, Roland; Fanjul Hevia, Víctor; Piñeiro Ugalde, Alejandro; Liang, Qi; Prosser, Haydn M.; Bradley, Allan; Cadiñanos Bañales, Juan; López Otín, Carlos
Showing results 16 to 35 of 38

 

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