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Showing results 3 to 22 of 38
Issue DateTitleAuthor(s)
2016Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterationsRivera Torres, José; Calvo, Conrado J.; Llach, A.; García Osorio, Fernando; López Otín, Carlos
2011Cell autonomous and systemic factors in progeria developmentGarcía Osorio, Fernando; Piñeiro Ugalde, Alejandro; Mariño García, Guillermo; Suárez Puente, Xosé Antón; Pérez Freije, José María; López Otín, Carlos
2018Changes at the nuclear lamina alter binding of pioneer factor Foxa2 in aged liverWhitton, H.; Singh, L. N.; Patrick, M. A.; Price, A. J.; García Osorio, Fernando; López Otín, Carlos; Bochkis, I. M.
2008Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature agingVarela Egocheaga, Ignacio Alejandro; Pereira, Sandrine; Piñeiro Ugalde, Alejandro; Navarro, Claire L.; Fernández Suárez, María; Cau, Pierre; Cadiñanos Bañales, Juan; García Osorio, Fernando; Foray, Nicolas; Cobo Plana, Juan Manuel; Carlos Villafranca, Félix Antonio de; Lévy, Nicolas; Pérez Freije, José María; López Otín, Carlos
2011A conserved splicing mechanism of the LMNA gene controls premature agingLópez Mejía, Isabel Cristina; Vautrot, Valentin; Toledo, Marion de; Behm-Ansmant, Isabelle; Bourgeois, Cyril F.; Navarro, Claire L.; García Osorio, Fernando; Pérez Freije, José María; Stevenin, James; Sandre-Giovannoli, Annachiara de; López Otín, Carlos
2013Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatmentVilla Bellosta, Ricardo; Rivera Torres, José; García Osorio, Fernando; Acín-Pérez, Rebeca; Enríquez, José Antonio; López Otín, Carlos; Andrés, Vicente
2017Deficient autophagy induces chondrocyte dysfunction through lamin a/c accumulation in aging and osteoarthritisLópez de Figueroa, P.; Nogueira Recalde, Uxía; Calamia, V.; García Osorio, Fernando; Lotz, M.; López Otín, Carlos; Blanco, Francisco J.; Carames, B.
2017Deficient autophagy induces chondrocyte senescence through lamin a/c accumulation in aging and osteoarthritisLópez de Figueroa, Paloma; Nogueira Recalde, Uxía; Calamia, V.; García Osorio, Fernando; Lotz, Martin; López Otín, Carlos; Blanco, Francisco J.; Carames, Beatriz
2017Deficient Autophagy Induces Lamin a/C Accumulation in Aging and OsteoarthritisLópez de Figueroa, Paloma; Nogueira Recalde, Uxía; García Osorio, Fernando; Lotz, Martin; López Otín, Carlos; Blanco, Francisco J.; Carames, Beatriz
2013Detection of nuclear envelope alterations in senescenceBárcena Fernández, Clea; García Osorio, Fernando; Pérez Freije, José María
2019Development of a CRISPR/Cas9-based therapy for Hutchinson–Gilford progeria syndromeSantiago Fernández, Olaya; García Osorio, Fernando; Quesada Fernández, Víctor; Rodríguez, Francisco; Basso, Sammy; Maeso, Daniel; Rolas, Loïc; Barkaway, Anna; Nourshargh, Sussan; Rodríguez Folgueras, Alicia; Pérez Freije, José María; López Otín, Carlos
2018Erratum to: NF-¿B activation impairs somatic cell reprogramming in ageing (Nature Cell Biology, (2015), 17, 8, (1004-1013), 10.1038/ncb3207)Soria Valles, Clara; García Osorio, Fernando; Gutiérrez Fernández, Ana Yolanda; De los Ángeles, A.; Bueno, Clara; Menéndez, P.; Martín Subero, J. I.; Daley, G. Q.; Pérez Freije, José María; López Otín, Carlos
2011Exome Sequencing and Functional Analysis Identifies BANF1 Mutation as the Cause of a Hereditary Progeroid SyndromeSuárez Puente, Xosé Antón; Quesada Fernández, Víctor; García Osorio, Fernando; Cabanillas Farpón, Rubén; Cadiñanos Bañales, Juan; Martínez Fraile, Julia; Rodríguez Ordóñez, Gonzalo; Álvarez Puente, Diana; Fanjul Fernández, Miriam; Lévy, Nicolas; Pérez Freije, José María; López Otín, Carlos; Gutiérrez Fernández, Ana Yolanda
2011Germ-line mutations in epidermal growth factor receptor (EGFR) are rare but may contribute to oncogenesis: A novel germ-line mutation in EGFR detected in a patient with lung adenocarcinomaCenteno Ramos, Irene; Blay Albors, Pilar; Santamaría Ruiz de Azúa, Íñigo; Astudillo González, María Aurora; Sánchez Pitiot, Ana Gloria; García Osorio, Fernando; González Arriaga, Patricia; Iglesias Llaca, Fernando; Menéndez Rodríguez, María Primitiva; Tardón García, Adonina; Pérez Freije, José María; Balbín Felechosa, Milagros
2013Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell cultureRivera Torres, José; Acín-Pérez, Rebeca; Cabezas-Sánchez, P.; García Osorio, Fernando; González-Gómez, Cristina; Megias, D.; Cámara, C.; López Otín, Carlos; Enríquez, José Antonio; Luque-García, J. L.; Andrés, Vicente
2017Immune and inflammatory responses to DNA damage in cancer and agingSoria Valles, Clara; López Soto, Alejandro; García Osorio, Fernando; López Otín, Carlos
2010Insulin-like growth factor 1 treatment extends longevity in a mouse model of human premature aging by restoring somatotroph axis functionMariño García, Guillermo; Piñeiro Ugalde, Alejandro; Fernández Fernández, Álvaro; García Osorio, Fernando; Fueyo Silva, Antonio Manuel; Pérez Freije, José María; López Otín, Carlos
2015Loss of GLUT4 induces metabolic reprogramming and impairs viability of breast cancer cellsGarrido Cuesta, Pablo; García Osorio, Fernando; Morán Suárez, Javier; Cabello, Estefanía; Alonso García, Ana; Pérez Freije, José María; González González, Celestino
2015Loss of MT1-MMP causes cell senescence and nuclear defects which can be reversed by retinoic acidGutiérrez Fernández, Ana Yolanda; Soria Valles, Clara; García Osorio, Fernando; Gutiérrez Abril, Jesús; Garabaya Fernández, Cecilia; Aguirre Quevedo, Alina; Fueyo Silva, Antonio Manuel; Fernández García, María de la Soledad; Suárez Puente, Xosé Antón; López Otín, Carlos
2016Loss of the proteostasis factor AIRAPL causes myeloid transformation by deregulating IGF-1 signalingGarcía Osorio, Fernando; Soria Valles, Clara; Santiago Fernández, Olaya; Pérez Freije, José María; López Otín, Carlos
Showing results 3 to 22 of 38

 

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